Quorum Sensing and Phytochemicals

Quorum Sensing and Phytochemicals

Most infectious diseases are caused by bacteria, which proliferate within quorum sensing (QS)-mediated biofilms. Efforts to block QS in bacteria and disrupt biofilms have enabled the identification of bioactive molecules that are also produced by plants. This mini review primarily focuses on natural QS inhibitors, which display potential for treating bacterial infections and also enhance the sa...

Antibiofilm activity and quorum sensing inhibitory potential of phytochemicals

Quorum Sensing in Microbial Virulence

Cell-to cell communication occurs via a signaling pathway referred to as quorum sensing. There are four main types of these systems according to the chemical nature of signal molecules used by microorganisms to elicit expression of target genes in response to environmental stimuli or need of microbial communities. Type I system acts by using acyl homoserine lactones as signals to trigger the ex...

Mini Review of Phytochemicals and Plant Taxa with Activity as Microbial Biofilm and Quorum Sensing Inhibitors.

Microbial biofilms readily form on many surfaces in nature including plant surfaces. In order to coordinate the formation of these biofilms, microorganisms use a cell-to-cell communication system called quorum sensing (QS). As formation of biofilms on vascular plants may not be advantageous to the hosts, plants have developed inhibitors to interfere with these processes. In this mini review, re...

Analysis of Quorum Sensing Inhibition and Phytochemicals in Different Extracts of Garlic

Usage of Allium sativum L. bulb (Amaryllidaceae) against the pathogenesis of Pseudomonas aeruginosa is an emphasized approach. However, biological response and safety of herbal extracts depend upon the processing methods and solvents used in preparation. In this study, various garlic bulb extracts (ethanol, ethyl acetate, methanol, acetone, chloroform, toluene, raw and heated) were prepared and...